ICU Weekly
Edition 07August 4, 2026

High-yield critical care science, written every week

Intensive-care medicine, written every week.

Papers, cases, and bedside-relevant updates — no hype, no sponsors, no affiliates. Only science that changes practice.

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Articles
03
Briefs
03
Pearls
04
min read
3
Dr. Caroline Teixeira Pinheiro
ICU Physician · Brasília · Brazil

Archive

07 Previous editions

  1. 07

    ICU Weekly #7: Capillary Refill Time Resuscitation & Preoxygenation Strategies

    Issue #7 reviews the clinical outcomes of CRT-guided resuscitation, preoxygenation comparison in critically ill patients, and limits of driving pressure limitation in ARDS.

    Sepsis ResuscitationAirway Management & PreoxygenationMechanical Ventilation in ARDS
    August 4, 20263 min read
  2. 06

    ICU Weekly #6: Right Ventricular Shock, NIV Failure Triggers, and Sepsis Endotypes

    Issue #6 explores translational gaps in acute RV failure models, failure predictors during high-flow nasal oxygen therapy, and moving beyond generic septic shock resuscitation bundles toward phenotypically driven critical care.

    Right Ventricular Failure in Severe ShockNon-Invasive Ventilation Failure TriggersSepsis Subphenotypes & Resuscitation
    June 16, 20264 min read
  3. 05

    ICU Weekly #5: TTM 2026 Consensus, AKI Fluid Stewardship & ARDS Neuromuscular Blockade

    An evidence-based weekly critical care update evaluating neuroprotection, acute kidney injury fluid resuscitation limits, and neuromuscular blockade in ARDS.

    Targeted Temperature ManagementFluid Stewardship & AKINeuromuscular Blockade in ARDS
    June 9, 20263 min read
  4. 04

    ICU Weekly #4: Noninvasive Support, Steroids in Septic Shock, and Delirium Bundles

    In Issue #4, we dive into landmark multicenter RCT data on High-Flow Nasal Oxygen vs NIV across 5 clinical phenotypes, protocol updates on pediatric and adult stress-dose hydrocortisone, and a comprehensive 2026 framework for ICU delirium prevention.

    High-Flow Nasal Oxygen vs NIV in Hypoxemic Respiratory FailureStress-Dose Corticosteroids in Septic ShockDelirium Prevention & Management in Critical Care
    June 2, 20264 min read
  5. 03

    Septic shock, lung imaging, and what the evidence says now

    Five evidence updates reshaping ICU practice: who dies earliest in septic shock and why, whether lung ultrasound outperforms the chest X-ray, whether driving pressure–guided ventilation moves the mortality needle — plus what the data says about enteral nutrition timing and AI early warning systems.

    Septic Shock PrognosisLung Ultrasound vs CXRDriving Pressure VentilationVasopressin Timing+2 more
    May 26, 20268 min read
  6. 02

    When biology tells us exactly where to look

    From endotype-guided endotoxin adsorption to presepsin-stratified immunotherapy, this edition traces a clear signal: the future of critical care is treating the right biology in the right person at the right moment.

    Endotoxin AdsorptionProcalcitonin + NEWS2Hyperactive DeliriumHFNO vs NIV+2 more
    May 18, 20266 min read
  7. 01

    Sepsis, ventilation, and what's new and trustworthy in the literature

    Inaugural edition with the studies that change what happens at the bedside — from ANDROMEDA-SHOCK-2 (which repositioned capillary refill time as a resuscitation target) to the 2026 Surviving Sepsis Campaign guidelines. No hype. Only evidence that changes practice.

    Sepsis ResuscitationProtective VentilationSSC Guidelines 2026ICU Delirium+2 more
    May 11, 20266 min read

About

Written by a physician, for physicians.

I'm an ICU physician, founder of Lupe Lab, and the writer of this newsletter. Each week I write, create, and design an edition around the science that's worth reading — papers that change practice, cases that teach, guidelines that move the needle. No fluff, no sponsors, no affiliates.

If you're an intensivist, a resident, or just curious about what's happening at the frontier of bedside science, this newsletter is for you.